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  Mipso   is a   North Carolina   quartet formed in   Chapel Hill   and known for combining a traditional   string band   format with close   harmony   and a variety of modern influences. The band is made up of Wood Robinson (Bass, Vocals), Jacob Sharp (Mandolin, Vocals), Joseph Terrell (Guitar, Vocals) and Libby Rodenbough (Fiddle, Vocals). Career [ edit ] UNC Years and "Mipso Trio" [ edit ] While students at  UNC-Chapel Hill , guitarist Joseph Terrell and mandolin player Jacob Sharp began performing at Chapel Hill open mic nights as an acoustic duo. With the idea of forming a band to play  folk  and  bluegrass , they approached bassist Wood Robinson, with whom Terrell had previously performed in a campus party band, Funkosaurus Rex. Billed as "Mipso Trio," the group began performing in 2011 at campus events and occasionally around North Carolina. After partnering with local Chapel Hill record label Robust Records, t...

  An   anti-CD22  immunotoxin   is a   monoclonal antibody   (targeting   CD22 ) linked to a   cytotoxic agent . They are being studied in the treatment of some types of   B-cell   cancer . They bind to CD22, a receptor  protein  on the surface of normal B cells and B-cell  tumors , and, upon internalization, kill the cells. Therapeutic immunotoxins that use Pseudomonas exotoxin [ edit ] As of August 2009, several anti-CD22 immunotoxins are undergoing clinical trials. CAT-3888 and CAT-8015 [ edit ] Main article:  Moxetumomab pasudotox CAT-3888  (or BL22) is an anti-CD22 immunotoxin and completed a  Phase I  clinical (human) trial for the treatment of  hairy cell leukemia [1]  at the  NIH  in the U.S. Technically, CAT-3888 is an anti-CD22 immunotoxin fusion protein between a murine anti-CD22 disulfide-linked Fv (dsFv)  antibody fragment  and an edited copy of bacterial Pseud...